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Micromixing Enhancement by Optimizing the Geometry of a Micromixer by Means of Response Surface Methodology: Application to Chemical Microreactors

[ Vol. 9 , Issue. 1 ]


Joaquin Ortega-Casanova* and Pablo Benitez-Alcaide   Pages 28 - 38 ( 11 )


Objecive: The Response Surface Methodology (RSM) is applied to optimize a passive micromixing unit according to three different targets.

Method: To that end several numerical simulations of the low Reynolds number flow in a micromixer, comprising a T-channel and a mixing unit in the main channel, have been conducted. The mixing is enhanced by means of two bars at known angles inside the mixing unit. The input parameter of the optimization process is the distance between bars and, depending on the desired target, different optimal separations are proposed. It has also been assessed how different mixing parameters change when multiple repetitions of the mixing unit, up to 10, are used in the microchannel.

Conclusion: This has allowed us to identify the use of 10 units as the best configuration to get the highest efficiency, but the use of 1 unit as the cheapest one, from a mixing cost point of view. Additionally, some configurations have also been assessed as potential chemical microreactors, and it will be shown that they perform better as microreactor than as micromixer.


Response surface, CFD, microchannel, laminar flow, mixing energy cost, T-channel, micromixer.


Universidad de Malaga, Andalucia Tech, Malaga, Universidad de Malaga, Andalucia Tech, Malaga

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