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Adhesive Transfer Soft Lithography: Low-Cost and Flexible Rapid Prototyping of Microfluidic Devices

[ Vol. 6 , Issue. 1 ]


Seung Hee Jeong, Klas Hjort and Zhigang Wu   Pages 42 - 49 ( 8 )


A simple and low-cost approach was proposed for prototyping PDMS based microfluidic devices by transferring adhesive film microstructures onto a flexible substrate as a mould for PDMS replicas. The microstructures were engraved on an adhesive coated film using a commercial cutting plotter and then transferred (or laminated) onto a flexible substrate, allowing for engraved isolated patterns. The proposed technique was demonstrated by a hydrodynamic focusing microfluidic device, having splitting and re-combining sheath channels. The whole processing could be finished within 1 h in a normal laboratory environment. This approach offers an easy, flexible and rapid prototyping of microfluidic and lab-on-a-chip devices to users without expertise in microfabrication. In addition, by minimizing the use of chemicals, the process becomes more environmentally friendly than conventional photolithography based micro-fabrication techniques.


Adhesive transfer, isolated structure replica, microfluidic device, rapid prototyping, soft lithography, tape transfer lithography.


Microsystems technology, Department of Engineering Sciences, Uppsala University, Box-534, The Angstrom Laboratory, SE-751 21, Uppsala, Sweden.

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